P-34 Feasibility for preimplantation genetic diagnosis after single cell biopsy in an infertile couple with calpainopathy
نویسندگان
چکیده
منابع مشابه
Blastocyst biopsy and preimplantation genetic diagnosis for single gene diseases: a turnaround on the horizon?
In this issue of RBM Online, two independent studies, Feng et al. (2012) and Lathi et al. (2012), confirm the conclusions of an earlier cohort study on comparative genomic hybridization (CGH) after trophectoderm biopsy and vitrification (Schoolcraft et al., 2010). Feng and co-workers demonstrate that vitrification and warming of blastocysts has minimal effect on their viability, while Lathi and...
متن کاملPreimplantation genetic diagnosis for a couple with recurrent pregnancy loss and triploidy.
BACKGROUND Triploidy may arise from fertilization of a mature haploid egg by two haploid sperm or by failure of meiotic divisions yielding a diploid gamete. We encountered a couple with habitual abortion, in which the last two fetuses were documented as viable triploid. METHODS To avoid dispermic penetration and development of abnormal preembryos, insemination was done by intracytoplasmic spe...
متن کاملNeonatal outcome after preimplantation genetic diagnosis.
OBJECTIVE To examine whether embryo biopsy for preimplantation genetic diagnosis (PGD) influences neonatal outcomes. DESIGN Prospective follow-up cohort. SETTING Tertiary university-affiliated medical center. PATIENT(S) 242 children born after PGD, 242 children born after intracytoplasmic sperm injection (ICSI) (158 singletons and 42 twins pairs in each group), and 733 children born after...
متن کاملPreimplantation genetic diagnosis and the biopsy technique: Important considerations
Preimplantation genetic diagnosis allows to test the genetic status of embryos prior to implantation. In order to obtain genetic material, on which carry out a genetic diagnosis, a procedure named embryo biopsy is required. In the last two decades, embryo biopsy at the cleavage stage has been the mostly performed procedure. However, recently, alternative methods allowing the retrieval of a larg...
متن کاملVitrified/warmed single blastocyst transfer in preimplantation genetic diagnosis/preimplantation genetic screening cycles.
OBJECTIVE To investigate the single blastocyst transfer in preimplantation genetic diagnosis (PGD)/preimplantation genetic screening (PGS) cycles. METHODS 80 PGD/PGS cycles undergoing blastocyst biopsy were studied. There were 88 warming cycles during the study period. Only one warmed blastocyst was transferred per cycle. The outcomes were followed up to the infants were born. RESULTS The e...
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ژورنال
عنوان ژورنال: Reproductive BioMedicine Online
سال: 2013
ISSN: 1472-6483
DOI: 10.1016/s1472-6483(13)60097-8